Service introduction

        DNA methylation is an important part of epigenetics, which plays an important role in maintaining normal cell function, genetic imprinting, embryonic development, and human tumor occurrence. Bisulfite treatment can distinguish unmethylated cytosine from methylated cytosine in the genome, and thus has become a classic experimental method in epigenetics research. The bisulfite treatment combined with high-throughput sequencing technology, the sequencing method of bisulfite sequencing, can draw a single-base resolution DNA methylation map. The analysis of the high-precision methylation modification patterns of specific species provides a foundation for the application in the basic mechanism research of cell differentiation, tissue development, and breeding, human health and disease research.

Technical procedures

Sample requirements and experiment cycle

Bioinformatics analysis